Studies & Reviews

Elderberry for immune support


Health Benefit

Significant reduction of Influenza B symptoms and faster cure

Study Type & Dosage

  • Cell assay & randomized, double-blind placebo-controlled study

  • Children: 2 tablespoons

  • Adults: 4 tablespoons

Excerpt from Publication

Inhibition of several strains of influenza virus in vitro. Treatment with elderberry extract during an outbreak of Influenza B/Panama elicited a significant improvement of the symptoms, including fever.*

Complete cure was achieved within 2 to 3 days in nearly 90% of the treated group and within at least 6 days in the placebo group (p < 0.001).*

Reference: Zakay-Rones et al, J Int Med Res. 2004 Mar-Apr;32(2):132-40. 


Health Benefit

Improvement of symptoms of Influenza A and B

Study Type & Dosage

  • Randomized, double-blind placebo-controlled study

  • 15 ml four times a day

Excerpt from Publication

Symptoms were relieved on average 4 days earlier and use of rescue medication was significantly less in those receiving elderberry extract compared with placebo. Elderberry extract seems to offer an efficient, safe and cost-effective treatment for influenza.*

Reference: Zakay-Rones et al, J Int Med Res. 2004 Mar-Apr;32(2):132-40. 


Health Benefit

A significant reduction of cold duration and severity in air travelers

Study Type & Dosage

  • Randomized, double-blind placebo-controlled study

  • Elderberry extract 600 mg extract/day 10 days prior until 1 day prior to travel, 900 mg/day 1 day prior until 4/5 days after arriving

Excerpt from Publication

Elderberry supplementation reduced cold duration and symptoms in air travelers. Placebo group participants had a significantly longer duration of cold episode days (117 vs. 57, p = 0.02) and the average symptom score over these days was also significantly higher (583 vs. 247, p = 0.05).*

Reference: Tiralongo et al. Nutrients. 2016 Apr; 8(4): 182. 


Health Benefit

Immune response stimulation and influenza virus suppression

Study Type & Dosage

  • Cell assay & animal (mice) study

  • 1 mg, 5 mg, and 10 mg/day

Excerpt from Publication

We evaluated the antiviral effect of concentrated juice of elderberry (CJ-E) on the human Influenza A virus (IFV). CJ-E had a relatively strong effect on IFV-infected mice. We conclude that CJ-E had a beneficial effect by the stimulating immune response and preventing viral infection.*

Reference: Kinoshita et al 2012, Biosci. Biotechnol. Biochem. 2015, 76 (9), 1633–1638 


Health Benefit

Inhibitory activity against clinically- relevant human respiratory bacterial pathogens and Influenza A & B

Study Type & Dosage

Cell assays

Excerpt from Publication

For the first time, it was shown that a standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. The liquid extract also displays an inhibitory effect on the propagation of human pathogenic influenza viruses.*

Reference: Krawitz et al, BMC Complement Altern Med. 2011 Feb 25;11:16 


Health Benefit

Antiviral, antimicrobial and general health properties

Study Type & Dosage

Review

Excerpt from Publication

shown the efficacy of S. nigra against select microbial pathogens. Multiple in vitro studies using standardized elderberry extracts have found them to inhibit influenza.*

Reference: Porter and Bode, Phytother Res. 2017 Apr;31(4):533-554. 


Health Benefit

Antioxidant effects, polyphenol content and absorption and various health benefits of elderberry

Study Type & Dosage

Review

Excerpt from Publication

Elderberry has medicinal properties associated with the presence of polyphenols, which are compounds with potential antioxidant properties. They can greatly affect the course of illness by counteracting oxidative stress, exerting beneficial effects on blood pressure, glycaemia reduction, immune system stimulation, antitumor potential, increase in the activity of antioxidant enzymes in the blood plasma, including also glutathione, and the reduction of uric acid levels.*

Reference: Sidor and Gramza-Michałowska Journal of Functional Foods 2015, Volume 18, Part B, Pages 757-1200 


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.


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